From Toronto Pearson International Airport:
- Take Highway 401 West to Highway 403 West to QEW (Queen Elizabeth Way)/Hamilton.
- Continue to Niagara.
- From QEW take Highway 420 (Falls/Bridge to USA) through three traffic lights.
- Proceed to Falls Avenue.

From Windsor, Ontario:
- Take Highway 401 East to Highway 403 East to QEW (Queen Elizabeth Way)/Niagara.
- Exit at Highway 420 and follow to Falls Avenue.

From Buffalo Niagara International Airport:
- Take Interstate 90 West to Exit 53 to 190 North.
- Exit at Peace Bridge (which is the bridge to Canada).
- Follow QEW (Queen Elizabeth Way) to Highway 420.
- Follow Highway 420 which becomes Falls Avenue.

From Barrie, Ontario:
- Take Highway 400 South to Highway 401 West.
- Take Highway 401 West to Highway 403 West to QEW (Queen Elizabeth Way)/Hamilton.
- Follow signs to QEW/Niagara. Exit at Highway 420 (also called Falls/Bridge to USA).
- Go through three traffic lights to Falls Avenue.